These speckles were co-expressed with ER1 (Figure 4, ICL) and ER2 (Figure 4, MCP); but while ER1 and -2 appearance tended to be more uniform across the nucleus, the S105-ER nuclear speckles formed discrete nuclear foci (Figure 4O)
These speckles were co-expressed with ER1 (Figure 4, ICL) and ER2 (Figure 4, MCP); but while ER1 and -2 appearance tended to be more uniform across the nucleus, the S105-ER nuclear speckles formed discrete nuclear foci (Figure 4O). partial ER-agonist genistein. S105-ER nuclear speckles were also seen in MCF-7 cells and markedly increased in size…