The fluorogenic substrate Ac-DEVD-AMC, which corresponds to the cleavage site found in executioner caspases targets, was used to measure the activation of these caspases
The fluorogenic substrate Ac-DEVD-AMC, which corresponds to the cleavage site found in executioner caspases targets, was used to measure the activation of these caspases. phase of the cell cycle having a concomitant increase in cell figures. Transient or stable overexpression of sphingosine kinase in NIH 3T3 fibroblasts or HEK293 cells safeguarded against apoptosis induced by…