Primary human T cells with two modifications were enriched by gating on the cells that had at least one modification, and this effect was consistent across multiple combinations of genomic loci
Primary human T cells with two modifications were enriched by gating on the cells that had at least one modification, and this effect was consistent across multiple combinations of genomic loci. viability and function. This permits individual or multiplexed modification of endogenous genes. First, we apply this strategy to correct a pathogenic mutation in cells…