Its up\regulation has been shown to be a poor prognostic indication in the majority of human tumors
Its up\regulation has been shown to be a poor prognostic indication in the majority of human tumors.3 Stimulants of VEGF production in tumor cells include hypoxia, hypoglycemia, and oncogenes such as ras, or inactivation of tumor suppressor genes such as p53 and the von Hippel\Lindau gene.2 For the most part, VEGF production is controlled by…