Profiling of B cell subsets over the vaccination program revealed that KLH-specific B cells matured from nave to class-switched memory space B cells, confirming the prototypic B cell response to a neo-antigen
Profiling of B cell subsets over the vaccination program revealed that KLH-specific B cells matured from nave to class-switched memory space B cells, confirming the prototypic B cell response to a neo-antigen. cells, confirming the prototypic B cell response to a neo-antigen. We conclude that flow-cytometric detection and in-depth phenotyping of KLH-specific B cells is…