A more recent study confirmed that GluA2 autoantibodies promote receptor internalization and a consequent decrease in synaptic GluA2-containing AMPARs [47]
A more recent study confirmed that GluA2 autoantibodies promote receptor internalization and a consequent decrease in synaptic GluA2-containing AMPARs [47]. alterations has been well addressed in animal studies. Overall, these preclinical studies have opened new avenues for the development of novel pharmacological treatments specifically targeting the synaptic activation of ionotropic glutamate receptors. Keywords:autoimmunity, glutamate, brain…